Partial and transient modulation of the CD3-T-cell receptor complex, elicited by low-dose regimens of monoclonal anti-CD3, is sufficient to induce disease remission in non-obese diabetic mice-Reference-Cited by-同舟云学术

Partial and transient modulation of the CD3-T-cell receptor complex, elicited by low-dose regimens of monoclonal anti-CD3, is sufficient to induce disease remission in non-obese diabetic mice

Published:2010-05 Issue:1 Volume:130 Page:103-113
ISSN:0019-2805
Container-title:Immunology
language:en
Short-container-title:

Author:

Mehta Devangi S.,Christmas Rudy A.,Waldmann Herman,Rosenzweig Michael

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2567.2009.03217.x/fullpdf

Reference24 articles.

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2. CD3-specific antibody-induced active tolerance: from bench to bedside;Chatenoud;Nat Rev Immunol,2003

3. TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+ CD25+ regulatory T cells responsible for protection against diabetes;Peng;Proc Natl Acad Sci USA,2004

4. Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment;You;Proc Natl Acad Sci USA,2007

5. Neonatal injection of CD3 antibody into nonobese diabetic mice reduces the incidence of insulitis and diabetes;Hayward;J Immunol,1989

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