Polyamine oxidase activity in rheumatoid arthritis synovial fluid-Reference-Cited by-同舟云学术

Polyamine oxidase activity in rheumatoid arthritis synovial fluid

Published:1990-06 Issue:3 Volume:80 Page:373-375
ISSN:1365-2249
Container-title:Clinical and Experimental Immunology
language:en
Short-container-title:

Author:

FERRANTE A¹,STORER R J¹,CLELAND L J²

Affiliation:

1. Department of Immunology and University Department of Paediatrics, Adelaide Children's Hospital, South Australia

2. Department of Rheumatology, Royal Adelaide Hospital, Adelaide, South Australia

Abstract

SUMMARY Oxidation of polyamides by polyamine oxidases (PAO) leads to the generation of highly reactive aminoaldehydes which have been shown to have a variety of effects, including killing of pathogenic microorganisms and regulation of leucocyte functions. Data presented here show that PAO are present in synovial fluid from patients with rheumatoid arthritis. This finding may have important implications in the various properties attributed to synovial fluid which includes anti-inflammatory activity

Publisher

Oxford University Press (OUP)

Subject

Immunology,Immunology and Allergy

Link

https://academic.oup.com/cei/article-pdf/80/3/373/42218137/j.1365-2249.1990.tb03295.x.pdf

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