The role of T helper type 17 cells in inflammatory arthritis-Reference-Cited by-同舟云学术

The role of T helper type 17 cells in inflammatory arthritis

Published:2009-08-25 Issue:3 Volume:159 Page:225-237
ISSN:1365-2249
Container-title:Clinical and Experimental Immunology
language:en
Short-container-title:

Author:

Sarkar S¹,Cooney L A²,Fox D A²

Affiliation:

1. Department of Medicine, Section of Rheumatology, University of Arizona Tucson, AZ

2. Program in Immunology and Rheumatic Diseases Research Core Center, University of Michigan Division of Rheumatology, Ann Arbor, MI, USA

Abstract

Summary While T cells have been implicated in the pathogenesis of inflammatory arthritis for more than three decades, the focus on the T helper type 17 (Th17) subset of CD4 T cells and their secreted cytokines, such as interleukin (IL)-17, is much more recent. Proinflammatory actions of IL-17 were first identified in the 1990s, but the delineation of a distinct Th17 subset in late 2005 has sparked great interest in the role of these cells in a broad range of immune-mediated diseases. This review summarizes current understanding of the role of Th17 cells and their products in both animal models of inflammatory arthritis and human immune-driven arthritides.

Publisher

Oxford University Press (OUP)

Subject

Immunology,Immunology and Allergy

Link

https://academic.oup.com/cei/article-pdf/159/3/225/41925444/j.1365-2249.2009.04016.x.pdf

Reference145 articles.

1. IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis;Lubberts;J Immunol,2001

2. IL-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses;Fujimoto;Arthritis Rheum,2008

3. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice;Nakae;J Immunol,2003

4. Treatment with a neutralizing anti-murine IL-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion;Lubberts;Arthritis Rheum,2004

5. Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with IL-17 receptor IgG1 Fc fusion protein;Bush;Arthritis Rheum,2002

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