The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis
Author:
Publisher
Wiley
Subject
Dermatology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2133.2008.08677.x/fullpdf
Reference20 articles.
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2. Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34;van Slegtenhorst;Science,1997
3. European Chromosome 16 Tuberous Sclerosis Consortium. Identification and characterization of the tuberous sclerosis gene on chromosome 16;Cell,1993
4. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling;Inoki;Nat Cell Biol,2002
5. Akt regulates growth by directly phosphorylating Tsc2;Potter;Nat Cell Biol,2002
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