Modulation of α1-acid glycoprotein (AGP) gene induction following honey bee venom administration to adjuvant arthritic (AA) rats; possible role of AGP on AA development-Reference-Cited by-同舟云学术

Modulation of α1-acid glycoprotein (AGP) gene induction following honey bee venom administration to adjuvant arthritic (AA) rats; possible role of AGP on AA development

Published:1993-10 Issue:1 Volume:94 Page:156-162
ISSN:0009-9104
Container-title:Clinical and Experimental Immunology
language:en
Short-container-title:

Author:

YIANGOU M¹,KONIDARIS C¹,VICTORATOS P¹,HADJIPHTROU-KOUROUNAKIS L¹

Affiliation:

1. Faculty of Sciences, School of Biology, Department of Genetics, Development and Molecular Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece

Abstract

SUMMARY Honey bee venom (HBV) administration to adjuvant arthritic (AA) rats resulted in a significant suppression of arthritis and in suppression of the hepatic acute phase α1-acid glycoprotein (AGP) gene induction at the early stages of disease development. AGP administration in AA rats resulted in acceleration of arthritis development and in increase of severity and duration of the disease. IL-1, IL-6. tumour necrosis factor (TNF) and glucocorticoids alone are not responsible for thc HBV-mediated AGP gene down-regulation. These results indicate that AGP gene expression in AA and HBV-treated AA rats involves the interaction of several factors, and that AGP plays a role for AA development in rats.

Publisher

Oxford University Press (OUP)

Subject

Immunology,Immunology and Allergy

Link

https://academic.oup.com/cei/article-pdf/94/1/156/42210667/j.1365-2249.1993.tb05994.x.pdf

Reference34 articles.

1. The phenomenon of the acute phase response;Kushner;Ann NY Acad Sci,1982

2. Hepatic acute phase reaction in vivo and in vitro;Baumann;Cell Dev Biol,1989

3. Leukocyte surface origin of human α1-acid glycoprotein (orosomucoid);Gahmberg;J Exp Med,1978

4. Interactions of α1-acid glycoprotein with the immune system;Chiu;Immunology,1977

5. Inhibitory effect of an antibody against alpha1-acid glycoprotein (α1-AGP) on autologous mixed lymphocyte reaction and anti-T3 lymphocyte activation;Stefanini;Cell Immunol,1986

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. REVIEW ON MEDICAL VALUES OF HONEY BEE VENOM AND THEIR BIOLOGICAL ACTION AND HEALTH BENEFITS;INDO AM J PHARM SCI;2019

2. Targeting TNF-α and NF-κB Activation by Bee Venom: Role in Suppressing Adjuvant Induced Arthritis and Methotrexate Hepatotoxicity in Rats;PLoS ONE;2013-11-20

3. Bee venom acupuncture for chronic low back pain: A randomised, sham-controlled, triple-blind clinical trial;European Journal of Integrative Medicine;2012-09

4. The nociceptive and anti-nociceptive effects of bee venom injection and therapy: A double-edged sword;Progress in Neurobiology;2010-10

5. α1-Acid glycoprotein production in rat dorsal air pouch in response to inflammatory stimuli, dexamethasone and honey bee venom;Experimental and Molecular Pathology;2010-08