A randomized, double-blind trial demonstrating bioequivalence of the current recombinant activated factor VII formulation and a new robust 25°C stable formulation

Author:

BYSTED B. V.,SCHARLING B.,MØLLER T.,HANSEN B. L.

Publisher

Wiley

Subject

Genetics(clinical),Hematology,General Medicine

Reference12 articles.

1. A cell-based model of hemostasis;Hoffman;Thromb Haemost,2001

2. Prospective, randomised trial of two doses of rFVIIa (NovoSeven) in haemophilia patients with inhibitors undergoing surgery;Shapiro;Thromb Haemost,1998

3. Activation of factor VII bound to tissue factor: a key early step in the tissue factor pathway of blood coagulation;Rao;Proc Natl Acad Sci USA,1988

4. Platelet activity of high-dose factor VIIa is independent of tissue factor;Monroe;Br J Haematol,1997

5. Activated factor VII activates factors IX and X on the surface of activated platelets: thoughts on the mechanism of action of high-dose activated factor VII;Hoffman;Blood Coagul Fibrinolysis,1998

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