Frequency of Mouse Double Minute 2 (MDM2) and Mouse Double Minute 4 (MDM4) amplification in parosteal and conventional osteosarcoma subtypes

Author:

Duhamel Laure A E,Ye Hongtao,Halai Dina,Idowu Bernadine D,Presneau Nadège,Tirabosco Roberto,Flanagan Adrienne M

Publisher

Wiley

Subject

General Medicine,Histology,Pathology and Forensic Medicine

Reference5 articles.

1. Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy;Tovar;Proc. Natl Acad. Sci. USA,2006

2. Immunohistochemical analysis of MDM2 and CDK4 distinguishes low-grade osteosarcoma from benign mimics;Yoshida;Mod. Pathol.,2010

3. Analysis of 12q13-15 genes in parosteal osteosarcoma;Gamberi;Clin. Orthop. Relat. Res.,2000

4. MDMX overexpression prevents p53 activation by the MDM2 inhibitor Nutlin;Hu;J. Biol. Chem.,2006

5. Characterization of the 12q15 MDM2 and 12q13-14 CDK4 amplicons and clinical correlations in osteosarcoma;Mejia-Guerrero;Genes Chromosom. Cancer,2010

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