The effects of diltiazem on hepatic drug metabolizing enzymes in man using antipyrine, trimethadione and debrisoquine as model substrates.

Author:

Sakai H.,Kobayashi S.,Hamada K.,Iida S.,Akita H.,Tanaka E.,Uchida E.,Yasuhara H.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference25 articles.

1. Substrate-selective inhibition by verapamil and diltiazem: differential disposition of antipyrine and theophylline in humans;Abernethy;J. Pharmac. exp. Ther.,1988

2. Polymorphism of debrisoquine hydroxylation among Finns and Lapps;Arvela;Br. J. clin. Pharmac.,1988

3. Changes in antipyrine and indo-cyanine green kinetics during nifedipine, verapamil and diltiazem therapy;Bauer;Clin. Pharmac. Ther.,1986

4. Interindividual differences in drug disposition: Clinical implications and methods of investigation;Breimer;Clin. Pharmacokin.,1983

5. Carbamazepine neurotoxicity precipitated by diltiazem;Brodie;Br. med. J.,1986

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