First‐in‐man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials-Reference-Cited by-同舟云学术

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First‐in‐man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

Published:2013-01-10 Issue:2 Volume:75 Page:535-548
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Moehrle Joerg J.¹,Duparc Stephan¹,Siethoff Christoph²,Giersbergen Paul L. M.²,Craft J. Carl¹,Arbe‐Barnes Sarah³,Charman Susan A.⁴,Gutierrez Maria⁵,Wittlin Sergio⁶,Vennerstrom Jonathan L.⁷

Affiliation:

1. Medicines for Malaria Venture Geneva Switzerland

2. Swiss BioQuant Reinach Switzerland

3. Aptiv Solutions Stevenage BioScience Catalyst Stevanage UK

4. Centre for Drug Candidate Optimisation Monash Institute of Pharmaceutical Sciences Parkville Australia

5. Comprehensive Phase One Miramar FL USA

6. Swiss Tropical and Public Health Institute Basel Switzerland

7. University of Nebraska Medical Center Omaha NE USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2125.2012.04368.x

Reference21 articles.

1. The paroxysm of Plasmodium vivax malaria

2. Artemisinin-based combinations

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