Pharmacokinetic comparison of inhaled fixed combinationvs. the free combination of beclomethasone and formoterol pMDIs in asthmatic children

Author:

Chawes Bo L. K.1,Piccinno Annalisa2,Kreiner-Møller Eskil1,Vissing Nadja H.1,Poorisrisak Porntiva1,Mortensen Li1,Nilson Erik1,Bisgaard Amalie1,Dossing Anna1,Deleuran Maja1,Skytt Nanna L.1,Samandari Nasim1,Sergio Francesco2,Ciurlia Giorgia2,Poli Gianluigi2,Acerbi Daniela2,Bisgaard Hans1

Affiliation:

1. Copenhagen University Hospital; Copenhagen Prospective Studies on Asthma in Childhood; Health Sciences; University of Copenhagen & Danish Pediatric Asthma Center; Gentofte; Denmark

2. Corporate Clinical Development; Chiesi Farmaceutici S.p.A.; Parma; Italy

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference12 articles.

1. Global Initiative for Asthma (GINA), National Institute of Health, National Heart Lung and Blood Institute (NHLBI) / World Health Organisation (WHO) Global strategy for asthma management and prevention 2012 http://www.ginasthma.org

2. Alan & Hanbury Ltd Seretide Summary of Product Characteristics; Symbicort Summary of Product Characteristics 2012 http://www.medicines.org.uk/emc/medicine/

3. Combination of inhaled long-acting beta2-agonists and inhaled steroids versus higher dose of inhaled steroids in children and adults with persistent asthma;Greenstone;Cochrane Database Syst Rev,2005

4. European Medicines Agency (EMEA) Guideline on the Investigation of Bioequivalence 2012

5. Design and Analysis of Cross-Over Trials

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