Bendamustine plus mitoxantrone for relapsed/refractory chronic lymphocytic leukaemia (CLL): results of a multicentre phase II study of the German CLL Study Group (GCLLSG)

Author:

Köppler Hubert1,Fuss Harald2,Hurtz Hans J.3,Knigge Owe4,Losem Christoph5,Reschke Daniel6,Schmitz Stephan7,Weide Rudolf1,Weiß Johann8,Hallek Michael9,

Affiliation:

1. Haematology/Oncology Group Practice; Koblenz Germany

2. Department of Internal Medicine III HELIOS Klinikum; Bad Saarow Germany

3. Haematology/Oncology Group Practice; Halle Germany

4. Department of Haematology/Oncology Klinikum; Frankfurt/Oder Germany

5. Haematology/Oncology Group Practice; Neuss Germany

6. Haematology/Oncology Group Practice; Oldenburg Germany

7. Haematology/Oncology Group Practice; Köln Germany

8. Haematology/Oncology Practice; Weiden Germany

9. Department I of Internal Medicine; Centre for Integrated Oncology (CIO) Köln-Bonn; University of Cologne; Cologne Germany

Funder

Mundipharma GmbH

Ribosepharm GmbH

Lederle

Publisher

Wiley

Subject

Hematology

Reference15 articles.

1. Sample size tables for exact single-stage phase II designs;A'Hern;Statistics in Medicine,2001

2. Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL;Badoux;Blood,2011

3. Efficacy of bendamustine in patients with relapsed or refractory chronic lymphocytic leukemia: results of a phase I/II study of the German CLL Study Group;Bergmann;Haematologica,2005

4. High rates of long-lasting remissions after 5-day bendamustine chemotherapy cycles in pre-treated low-grade non-Hodgkin's-lymphomas;Bremer;Journal of Cancer Research Clincal Oncology,2002

5. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment;Cheson;Blood,1996

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