TP53 pathway analysis in paediatric Burkitt lymphoma reveals increased MDM4 expression as the only TP53 pathway abnormality detected in a subset of cases

Author:

Leventaki Vasiliki1,Rodic Vladimir1,Tripp Sheryl R.2,Bayerl Michael G.3,Perkins Sherrie L.,Barnette Phillip4,Schiffman Joshua D.,Miles Rodney R.

Affiliation:

1. Department of Pathology; University of Utah Health Sciences Center; Salt Lake City; UT; USA

2. ARUP Laboratories Institute for Clinical and Experimental Pathology; Salt Lake City; UT; USA

3. Department of Pathology; Penn State College of Medicine; Hershey; PA; USA

4. Department of Pediatric Hematology/Oncology; University of Utah; Salt Lake City; UT; USA

Publisher

Wiley

Subject

Hematology

Reference42 articles.

1. Significance of HDMX-S (or MDM4) mRNA splice variant overexpression and HDMX gene amplification on primary soft tissue sarcoma prognosis;Bartel;International Journal of Cancer,2005

2. The pattern of p53 mutations in Burkitt's lymphoma differs from that of solid tumors;Bhatia;Cancer Research,1992

3. MDM4 (MDMX) is overexpressed in chronic lymphocytic leukaemia (CLL) and marks a subset of p53wild-type CLL with a poor cytotoxic response to Nutlin-3;Bo;British Journal of Haematology,2010

4. Long-term follow-up of short intensive multiagent chemotherapy without high-dose methotrexate (‘Orange’) in children with advanced non-lymphoblastic non-Hodgkin's lymphoma: a children's cancer group report;Cairo;Leukemia,2002

5. Results of a randomized international study of high-risk central nervous system B non-Hodgkin lymphoma and B acute lymphoblastic leukemia in children and adolescents;Cairo;Blood,2007

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3