Identification of three new compounds that directly target human serine hydroxymethyltransferase 2-Reference-Cited by-同舟云学术

Identification of three new compounds that directly target human serine hydroxymethyltransferase 2

Published:2020-09-16 Issue:2 Volume:97 Page:221-230
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Han Yanfang¹,He Liping¹,Qi Yifei¹²,Zhao Yue¹,Pan Yue¹,Fang Bohuan¹,Li Sha³,Zhang John Z. H.¹²⁴,Zhang Lujia¹²^ORCID

Affiliation:

1. Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development School of Chemistry and Molecular Engineering East China Normal University Shanghai China

2. NYU‐ECNU Center for Computational Chemistry at NYU Shanghai Shanghai China

3. State Key Laboratory of Materials‐Oriented Chemical Engineering Nanjing Tech University Nanjing China

4. Department of Chemistry New York University New York NY USA

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cbdd.13774

Reference41 articles.

1. Pyridoxal 5-Phosphate Enzymes as Targets for Therapeutic Agents

2. Serine and glycine metabolism in cancer

3. On the Mechanism of Action of Folate-And Biopterin-Requiring Enzymes

4. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed

5. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway

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