LAT1‐specific inhibitor is effective against T cell‐mediated allergic skin inflammation-Reference-Cited by-同舟云学术

LAT1‐specific inhibitor is effective against T cell‐mediated allergic skin inflammation

Published:2019-09-03 Issue:2 Volume:75 Page:463-467
ISSN:0105-4538
Container-title:Allergy
language:en
Short-container-title:Allergy

Author:

Hayashi Keitaro¹^ORCID,Kaminuma Osamu²³⁴^ORCID,Nishimura Tomoe⁴,Saeki Mayumi⁴,Matsuoka Kunie⁵,Hiroi Takachika⁴,Jutabha Promsuk¹,Iwata Yohei⁶,Sugiura Kazumitsu⁶,Owada Takayoshi⁷,Kurasawa Kazuhiro⁷,Okayasu Isao⁸,Ouchi Motoshi¹,Fujita Tomoe¹,Kanai Yoshikatsu⁹,Endou Hitoshi¹⁰,Anzai Naohiko¹¹¹

Affiliation:

1. Department of Pharmacology and Toxicology Dokkyo Medical University School of Medicine Shimotsuga Japan

2. Department of Disease Model, Research Institute of Radiation Biology and Medicine Hiroshima University Hiroshima Japan

3. Center for Life Science Research University of Yamanashi Yamanashi Japan

4. Allergy and Immunology Project Tokyo Metropolitan Institute of Medical Science Tokyo Japan

5. Mammalian Genetics Project Tokyo Metropolitan Institute of Medical Science Tokyo Japan

6. Department of Dermatology Fujita Health University School of Medicine Toyoake Japan

7. Department of Rheumatology Dokkyo Medical University School of Medicine Shimotsuga Japan

8. Kiryu University Midori Japan

9. Department of Bio‐system Pharmacology, Graduate School of Medicine Osaka University Suita Japan

10. J‐Pharma Co., Ltd. Yokohama Japan

11. Department of Pharmacology Chiba University Graduate School of Medicine Chiba Japan

Funder

Japan Society for the Promotion of Science

Shimabara Science Promotion Foundation

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/all.14019

Reference8 articles.

1. Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)

2. First-in-human phase I study of JPH203, L-type amino acids transporter 1 inhibitor, in patients with advanced solid tumors.

3. LAT1 Is a Critical Transporter of Essential Amino Acids for Immune Reactions in Activated Human T Cells

4. Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

5. The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies

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