Multiplexed cellular profiling identifies an organoselenium compound as an inhibitor of CRM1 ‐mediated nuclear export

Author:

Jimenez Lucia1,Mayoral‐Varo Victor1,Amenábar Carlos12,Ortega Judit1,Sequeira João G. N.3ORCID,Machuqueiro Miguel3ORCID,Mourato Cristiana45ORCID,Silvestri Romano6,Angeli Andrea7,Carta Fabrizio7,Supuran Claudiu T.7,Megías Diego8,Ferreira Bibiana I.45ORCID,Link Wolfgang1ORCID

Affiliation:

1. Cancer Biology Department Instituto de Investigaciones Biomédicas “Alberto Sols” (CSIC‐UAM) Madrid Spain

2. Departamento de Bioquímica Universidad Autónoma de Madrid (UAM) Madrid Spain

3. BioISI––Instituto de Biosistemas e Ciências Integrativas, Faculdade de Ciências Universidade de Lisboa Lisbon Portugal

4. ABC‐RI, Algarve Biomedical Center Research Institute Algarve Biomedical Center Faro Portugal

5. Faculty of Medicine and Biomedical Sciences University of Algarve Faro Portugal

6. Laboratory Affiliated with the Institute Pasteur Italy‐Cenci Bolognetti Foundation, Department of Drug Chemistry and Technologies Sapienza University of Rome Rome Italy

7. Università degli Studi di Firenze, NEUROFARBA Dept. Sezione di Farmaceutica e Nutraceutica Florence Italy

8. Advanced Optical Microscopy Unit Instituto de salud Carlos III Madrid Spain

Funder

FCT

Publisher

Wiley

Subject

Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology

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