1. Center for Computational Biology, Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA
2. Howard Hughes Medical Institute, Center for Advanced Biotechnology and Medicine, University of Medicine and Dentistry of New Jersey‐Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
3. Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA
4. Howard Hughes Medical Institute, Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA