1. Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, CA 92093‐0365, USA
2. Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093‐0365, USA
3. School of Biological Sciences, Queen’s University Belfast, Medical Biology Centre, Belfast BT9 7BL, UK
4. Department of Chemistry and Biochemistry, NSF Center for Theoretical Biological Physics, National Biomedical Computation Resource, University of California San Diego, La Jolla, CA 92093, USA
5. Department of Pharmacology, University of California San Diego, La Jolla, CA 92093, USA
6. Howard Hughes Medical Institute, University of California San Diego, La Jolla, CA 92093, USA