Exploration of Potential Prodrugs of RWJ-445167, an Oxyguanidine-based Dual Inhibitor of Thrombin and Factor Xa-Reference-Cited by-同舟云学术

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Exploration of Potential Prodrugs of RWJ-445167, an Oxyguanidine-based Dual Inhibitor of Thrombin and Factor Xa

Published:2006-07 Issue:1 Volume:68 Page:29-36
ISSN:1747-0277
Container-title:Chemical Biology Drug Design
language:en
Short-container-title:Chem Biol Drug Design

Author:

Maryanoff Bruce E.,McComsey David F.,Costanzo Michael J.,Yabut Stephen C.,Lu Tianbao,Player Mark R.,Giardino Edward C.,Damiano Bruce P.

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference44 articles.

1. New anticoagulants: beyond heparin, low-molecular-weight heparin and warfarin

2. Anticoagulant drugs: an update

3. Pharmacology and Clinical Potential of Direct Thrombin Inhibitors

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1. Rational In Silico Design of Selective TMPRSS6 Peptidomimetic Inhibitors via Exploitation of the S2 Subpocket;Journal of Medicinal Chemistry;2024-07-19

2. A Novel Prodrug Strategy Based on Reversibly Degradable Guanidine Imides for High Oral Bioavailability and Prolonged Pharmacokinetics of Broad-Spectrum Anti-influenza Agents;ACS Central Science;2024-07-04

3. Conformation Based in silico Studies of Cyclic Tetrapeptides with βγ Fused Turns as Thrombin Inhibitors;ChemistrySelect;2023-03-14

4. Emerging fluorination methods in organic chemistry relevant for life science application;Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals;2019

5. Advances in Anticoagulants;Comprehensive Medicinal Chemistry III;2017

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