Comparison of the Non-Nucleoside Reverse Transcriptase Inhibitor Lersivirine with its Pyrazole and Imidazole Isomers-Reference-Cited by-同舟云学术

Comparison of the Non-Nucleoside Reverse Transcriptase Inhibitor Lersivirine with its Pyrazole and Imidazole Isomers

Published:2011-03-29 Issue:5 Volume:77 Page:393-397
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:

Author:

Jones Lyn H.,Allan Gill,Corbau Romuald,Middleton Donald S.,Mowbray Charles E.,Newman Sandra D.,Phillips Chris,Webster Rob,Westby Mike

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference16 articles.

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3. Lersivirine: a non-nucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus-1;Corbau;Antimicrob Agents Chemother,2010

4. Mutational analysis of Trp-229 of human immunodeficiency virus type 1 reverse transcriptase (RT) identifies this amino acid residue as a prime target for the rational design of new non-nucleoside RT inhibitors;Pelemans;Mol Pharm,2000

5. Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. design, synthesis and biological evaluation of novel, potent and broad spectrum NNRTIs with antiviral activity;Fattorusso;J Med Chem,2005

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