A Thermodynamic Approach to the Affinity Optimization of Drug Candidates
Author:
Publisher
Wiley
Subject
Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry
Reference19 articles.
1. Adaptive inhibitors of the HIV-1 protease;Ohtaka;Prog Biophys Mol Biol,2005
2. Binding thermodynamics of statins to HMG-CoA reductase;Carbonell;Biochemistry,2005
3. Overcoming roadblocks in lead optimization: a thermodynamic perspective;Ruben;Chem Biol Drug Des,2006
4. Binding thermodynamics of substituted diaminopyrimidine renin inhibitors;Sarver;Anal Biochem,2007
5. Calorimetry and thermodynamics in drug design;Chaires;Annu Rev Biophys,2008
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