Quantitative Structure-Activity Relationship Models for Predicting Biological Properties, Developed by Combining Structure- and Ligand-Based Approaches: An Application to the Human Ether-a-go-go-Related Gene Potassium Channel Inhibition

Author:

Coi Alessio,Massarelli Ilaria,Saraceno Marilena,Carli Niccolò,Testai Lara,Calderone Vincenzo,Bianucci Anna Maria

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference126 articles.

1. A family of potassium channel genes related to eag in Drosophila and mammals;Warmke;Proc Natl Acad Sci USA,1994

2. HERG, a human inward rectifier in the voltage-gated potassium channel family;Trudeau;Science,1995

3. Ventricular arrhythmias. A potential risk associated with the use of non-cardiovascular drugs prolonging the QT interval;Calderone;Minerva Med,2002

4. Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit;Barry;Circ Res,1998

5. Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype;Jeron;Am J Physiol Heart Circ Physiol,2000

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3