Natural Borneol Enhances Paclitaxel-Induced Apoptosis of ESCC Cells by Inactivation of the PI3K/AKT

Author:

Meng Xiaofeng12,Dong Xiaomei1,Wang Wen12,Yang Liu12,Zhang Xia12,Li Yanfang3,Chen Tianfeng4,Ma Hang5,Qi Da6,Su Jianyu123ORCID

Affiliation:

1. School of Food Science and Engineering; South China Univ. of Technology; Guangzhou 510640 China

2. Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety; South China Univ. of Technology; Guangzhou 510640 China

3. Dept. of Nutrition and Food Science; Univ. of Maryland; College Park MD 20742 USA

4. Dept. of Chemistry; Jinan Univ.; Guangzhou 510632 China

5. Bioactive Botanical Research Laboratory, Dept. of Biomedical and Pharmaceutical Sciences, College of Pharmacy; Univ. of Rhode Island; Kingston RI 02881 USA

6. BGI-Shenzhen; Shenzhen 518083 China

Funder

Fundamental Research Funds for the Central Universities

Yang Fan Innovative & Entrepreneurial Research Team Project

Science and Technology Planning Project of Guangdong province

National Natural Science Foundation of China

Science and Technology Program of Guangzhou

National Key Research and Development Program of China

Publisher

Wiley

Subject

Food Science

Reference42 articles.

1. Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration;Cai;Journal of Drug Targeting,2008

2. Natural borneol enhances bisdemethoxycurcumin-induced cell cycle arrest in the G2/M phase through up-regulation of intracellular ROS in HepG2 cells;Chen;Food and Function,2014

3. Proteomic analysis of G2/M arrest triggered by natural borneol/curcumin in HepG2 cells, the importance of the reactive oxygen species-p53 pathway;Chen;Journal of Agriculture and Food Chemistry,2015

4. Effect of absorption enhancer of borneol on ginsenoside Rg1 and the nasal ciliotoxicity;Chen;Chinese Pharmaceutical Journal,2006

5. Phase II study and long-term follow-up of patients treated with taxol for advanced ovarian adenocarcinoma;Einzig;Journal of Clinical Oncology: official Journal of the American Society of Clinical Oncology,1992

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