Dimethyl fumarate ameliorates myoclonus stemming from protein misfolding in oligodendrocytes

Author:

Southwood Cherie M.1,Garshott Danielle M.2,Richardson Chelsea R.1,Seraji-Bozorgzad Navid3,Fribley Andrew M.2,Gow Alexander123ORCID

Affiliation:

1. Center for Molecular Medicine and Genetics; Wayne State University School of Medicine; Detroit MI USA

2. Carman and Ann Adams Department of Pediatrics; Wayne State University School of Medicine; Detroit MI USA

3. Department of Neurology; Wayne State University School of Medicine; Detroit MI USA

Funder

Biogen

National Multiple Sclerosis Society

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference52 articles.

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2. Increased axonal mitochondrial activity as an adaptation to myelin deficiency in the Shiverer mouse;Andrews;J. Neurosci. Res.,2006

3. Impaired glutathione synthesis in neurodegeneration;Aoyama;Int. J. Mol. Sci.,2013

4. Oral fumaric acid esters for psoriasis;Atwan;Cochrane Database Syst. Rev.,2015

5. Modulation of rumpshaker phenotype with wild-type PLP/DM20 suggests several pathogenic mechanisms;Barrie;J. Neurosci. Res.,2010

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