Causal inference for planning randomised critical care trials: Protocol for a scoping review

Author:

Kaas‐Hansen Benjamin Skov12ORCID,Granholm Anders1ORCID,Anthon Carl Thomas1ORCID,Kjær Maj‐Brit Nørregaard1ORCID,Sivapalan Praleene1ORCID,Maagaard Mathias3ORCID,Schjørring Olav Lilleholt45ORCID,Fagerberg Steen Kåre4ORCID,Ellekjær Karen Louise1ORCID,Mølgaard Jesper6ORCID,Ekstrøm Claus Thorn2ORCID,Møller Morten Hylander1ORCID,Perner Anders1ORCID

Affiliation:

1. Department of Intensive Care Copenhagen University Hospital Copenhagen Denmark

2. Section for Biostatistics, Department of Public Health University of Copenhagen Copenhagen Denmark

3. Department of Anaesthesiology, Centre for Anaesthesiological Research, Zealand University Hospital Køge Køge Denmark

4. Department of Anaesthesia and Intensive Care Aalborg University Hospital Aalborg Denmark

5. Department of Clinical Medicine Aalborg University Aalborg Denmark

6. Department of Anesthesiology, Centre for Cancer and Organ Dysfunction Copenhagen University Hospital Copenhagen Denmark

Funder

Dagmar Marshalls Fond

Grosserer Jakob Ehrenreich og Hustru Grete Ehrenreichs Fond

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine,General Medicine

Reference33 articles.

1. Delta inflation: a bias in the design of randomized controlled trials in critical care medicine

2. Powering Bias and Clinically Important Treatment Effects in Randomized Trials of Critical Illness*

3. FDA.Enrichment strategies for clinical trials to support determination of effectiveness of human drugs and biological products: guidance for industry.2019.https://www.fda.gov/regulatory‐information/search‐fda‐guidance‐documents/enrichment‐strategies‐clinical‐trials‐support‐approval‐human‐drugs‐and‐biological‐products.

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