Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results-Reference-Cited by-同舟云学术

Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results

Published:2018-07-12 Issue:8 Volume:59 Page:1540-1548
ISSN:0013-9580
Container-title:Epilepsia
language:en
Short-container-title:Epilepsia

Author:

Szaflarski Jerzy P.¹^ORCID,Bebin Elizabeth Martina¹,Comi Anne M.²,Patel Anup D.³^ORCID,Joshi Charuta⁴^ORCID,Checketts Daniel⁵,Beal Jules C.⁶^ORCID,Laux Linda C.⁷,De Boer Lisa M.⁸,Wong Matthew H.⁹,Lopez Merrick¹⁰,Devinsky Orrin¹¹,Lyons Paul D.¹²,Zentil Pilar Pichon¹⁰,Wechsler Robert¹³,

Affiliation:

1. University of Alabama Birmingham; Birmingham AL USA

2. Kennedy Krieger Institute; Baltimore MD USA

3. Nationwide Children's Hospital; Columbus OH USA

4. University of Iowa Children's Hospital; Iowa City IA USA

5. GW Research Ltd; London UK

6. Montefiore Medical Center and Albert Einstein College in Medicine; Bronx NY USA

7. Ann & Robert H. Lurie Children's Hospital of Chicago; Chicago IL USA

8. Greenwich Biosciences Inc.; Carlsbad CA USA

9. Wake Forest Baptist Medical Center; Winston-Salem NC USA

10. Loma Linda University Children's Hospital; Loma Linda CA USA

11. NYU Langone's Comprehensive Epilepsy Center; New York NY USA

12. Virginia Comprehensive Epilepsy Program; Winchester VA USA

13. Consultants in Epilepsy & Neurology; PLLC and Idaho Comprehensive Epilepsy Center; Boise ID USA

Funder

Alabama General Funds

GW Research Ltd

New York State Department of Health

Epilepsy Foundation

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/epi.14477/fullpdf

Reference17 articles.

1. Trial of cannabidiol for drug-resistant seizures in the Dravet syndrome;Devinsky;N Engl J Med,2017

2. Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial;Devinsky;Lancet Neurol,2016

3. Cannabidiol (CBD) significantly reduces drop seizure frequency in Lennox-Gastaut syndrome (LGS): results of a dose-ranging, multi-center, randomized, double-blind, placebo-controlled trial (GWPCARE3);Patel;Neurology,2017

4. Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial;Thiele;Lancet,2018

5. Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures;Jones;Seizure,2012

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