Safety profile of intravenous and subcutaneous siplizumab, an anti-CD2 monoclonal antibody, for the treatment of plaque psoriasis: results of two randomized, double-blind, placebo-controlled studies-Reference-Cited by-同舟云学术

Safety profile of intravenous and subcutaneous siplizumab, an anti-CD2 monoclonal antibody, for the treatment of plaque psoriasis: results of two randomized, double-blind, placebo-controlled studies

Published:2010-06-21 Issue:7 Volume:49 Page:818-828
ISSN:0011-9059
Container-title:International Journal of Dermatology
language:en
Short-container-title:

Author:

Langley Richard G.,Papp Kim,Bissonnette Robert,Toth Darryl,Matheson Robert,Hultquist Micki,White Barbara

Publisher

Wiley

Subject

Dermatology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-4632.2010.04512.x/fullpdf

Reference41 articles.

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4. The majority of epidermal T cells in psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: A type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients;Austin;J Invest Dermatol,1999

5. Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and “type 1” inflammatory gene expression;Lew;Trends Immunol,2004

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