Novel neuroactive steroid with hypnotic and T‐type calcium channel blocking properties exerts effective analgesia in a rodent model of post‐surgical pain-Reference-Cited by-同舟云学术

Novel neuroactive steroid with hypnotic and T‐type calcium channel blocking properties exerts effective analgesia in a rodent model of post‐surgical pain

Published:2020-01-23 Issue:8 Volume:177 Page:1735-1753
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Joksimovic Sonja Lj.¹²^ORCID,Joksimovic Srdjan M.¹,Manzella Francesca M.¹³,Asnake Betelehem⁴,Orestes Peihan¹,Raol Yogendra H.⁵,Krishnan Kathiresan⁶,Covey Douglas F.⁶⁷,Jevtovic‐Todorovic Vesna¹,Todorovic Slobodan M.¹³^ORCID

Affiliation:

1. Department of AnesthesiologyUniversity of Colorado Denver, Anschutz Medical Campus Aurora Co USA

2. Pharmacology Graduate Program, Faculty of PharmacyUniversity of Belgrade Belgrade Serbia

3. Neuroscience Graduate ProgramUniversity of Colorado Denver, Anschutz Medical Campus Aurora CO USA

4. Department of Anesthesiology and Pain MedicineUniversity of California Davis CA USA

5. Department of Pediatrics, Division of Neurology, Translational Epilepsy Research ProgramWashington University School of Medicine St. Louis MO USA

6. Department of Developmental BiologyWashington University School of Medicine St. Louis MO USA

7. Taylor Family Institute for Innovative Psychiatric ResearchWashington University School of Medicine St. Louis MO USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.14930

Reference61 articles.

1. Morphine, But Not Inhalation Anesthesia, Blocks Post-injury Facilitation The Role of Preemptive Suppression of Afferent Transmission

2. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels

3. Postoperative Pain Experience: Results from a National Survey Suggest Postoperative Pain Continues to Be Undermanaged

4. A neurosteroid analogue with T-type calcium channel blocking properties is an effective hypnotic, but is not harmful to neonatal rat brain

5. Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone

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