The genome of the medicinal plantAndrographis paniculataprovides insight into the biosynthesis of the bioactive diterpenoid neoandrographolide

Author:

Sun Wei1ORCID,Leng Liang1,Yin Qinggang1,Xu MeiMei2,Huang Mingkun1,Xu Zhichao3,Zhang Yujun1,Yao Hui3,Wang Caixia1,Xiong Chao1,Chen Sha1,Jiang Chunhong4,Xie Ning4,Zheng Xilong5,Wang Ying6,Song Chi1,Peters Reuben J.2,Chen Shilin1

Affiliation:

1. Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine; China Academy of Chinese Medical Sciences; Institute of Chinese Materia Medica; 100070 Beijing China

2. Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology; Iowa State University; Ames IA 50011-1079 USA

3. Key Laboratory of Bioactive Substances and Resources; Utilization of Chinese Herbal Medicine; Ministry of Education; Institute of Medicinal Plant Development; Chinese Academy of Medical Sciences & Peking Union Medical College; 100193 Beijing China

4. State Key Laboratory of Innovative Natural Medicine and TCM Injections; Jiangxi Qingfeng Pharmaceutical Co. Ltd.; 341008 Ganzhou China

5. Hainan Branch; Institute of Medicinal Plant Development; 570311 Wanning China

6. Wuhan Benagen Tech Solutions Company Limited; 430070 Wuhan China

Funder

National Natural Science Foundation of China

National Institutes of Health

National Postdoctoral Program for Innovative Talents Fund

Publisher

Wiley

Subject

Cell Biology,Plant Science,Genetics

Reference112 articles.

1. Anticancer and immunostimulatory compounds from Andrographis paniculata;Ajaya Kumar;J. Ethnopharmacol.,2004

2. Inhibitory effect of andrographolide from Andrographis paniculata on PAF-induced platelet aggregation;Amroyan;Phytomedicine,1999

3. A review on medicinal prospectives of Andrographis paniculata Nees;Anju;J. Pharm. Sci. Innov.,2012

4. In vitro cytogenetic effects of Andrographis paniculata (kalmegh) on arsenic;Avani;Phytomedicine,2008

5. P450s controlling metabolic bifurcations in plant terpene specialized metabolism;Banerjee;Phytochem. Rev.,2018

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