Mpox vaccination routes: prevalence, correlates and adverse effects of subcutaneous versus intradermal vaccination at a mass vaccination clinic in Sydney, Australia

Author:

Pollack Alisa1ORCID,Lo Winston1,Imamura Hanaho1,Caterson Ian12

Affiliation:

1. Vaccination Clinic Royal Prince Alfred Hospital Sydney New South Wales Australia

2. Boden Collaboration Charles Perkins Centre, The University of Sydney Sydney New South Wales Australia

Abstract

AbstractThe Royal Prince Alfred Hospital Mpox Vaccination Clinic opened in response to the 2022 multicountry mpox outbreak. A total of 9500 vaccinations were administered intradermally and subcutaneously during the first 16 weeks of clinic operation. The rate of adverse events was 0.1%. Compared to people who received the vaccine intradermally, those who received it subcutaneously were more likely to be aged 30–39 years (P = 0.047), sexual partners of gay and bisexual men (P < 0.001), eligible for Medicare (P < 0.001) and born in the Philippines (P = 0.01) or Malaysia (P = 0.04).

Publisher

Wiley

Reference15 articles.

1. World Health Organization.Mpox (Monkeypox). World Health Organization. Updated 18 April 2023. Available from URL:https://www.who.int/news-room/fact-sheets/detail/monkeypox.

2. Monkeypox

3. Commonwealth of Australia.Mpox (Monkeypox). Department of Health and Aged Care. Updated 29 September 2022. Available from URL:https://www.health.gov.au/diseases/monkeypox-mpox.

4. World Health Organization.Multi‐Country Outbreak of Mpox External Situation Report #31 – 22 December 2023. World Health Organization. Published 22 December 2023. Available from URL:https://www.who.int/publications/m/item/multi-country-outbreak-of-mpox--external-situation-report-31---22-december-2023.

5. National Notifiable Disease Surveillance System.National Communicable Disease Surveillance Dashboard. Department of Health and Aged Care. Updated 2 February 2024. Available from URL:https://nindss.health.gov.au/pbi-dashboard/.

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