Inulavosin and its benzo-derivatives, melanogenesis inhibitors, target the copper loading mechanism to the active site of tyrosinase

Author:

Fujita Hideaki123,Menezes José C. J. M. D. S.45,Santos Sérgio M.6,Yokota Sadaki1,Kamat Shrivallabh P.5,Cavaleiro José A. S.4,Motokawa Tomonori7,Kato Tomomi7,Mochizuki Mayu7,Fujiwara Toshiyuki1,Fujii Yuki1,Tanaka Yoshitaka28

Affiliation:

1. Section of Functional Morphology; Faculty of Pharmaceutical Sciences; Nagasaki International University; Nagasaki Japan

2. Division of Pharmaceutical Cell Biology; Graduate School of Pharmaceutical Sciences; Kyushu University; Fukuoka Japan

3. Innovation Center for Medical Redox Navigation; Kyushu University; Fukuoka Japan

4. Department of Chemistry and QOPNA; University of Aveiro; Aveiro Portugal

5. Department of Chemistry; Goa University; Taleigao, Goa India

6. Department of Chemistry and CICECO; University of Aveiro; Aveiro Portugal

7. Skin Research Department; POLA Chemical Industries, Inc.; Totsuka-ku, Yokohama Japan

8. Organelle Homeostasis Research Center; Kyushu University; Fukuoka Japan

Publisher

Wiley

Subject

Dermatology,General Biochemistry, Genetics and Molecular Biology,Oncology

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