Loss ofCDKN2Aexpression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines

Author:

Young Richard J.1,Waldeck Kelly1,Martin Claire1,Foo Jung H.1,Cameron Donald P.1,Kirby Laura1,Do Hongdo23,Mitchell Catherine2,Cullinane Carleen14,Liu Wendy1,Fox Stephen B.24,Dutton-Regester Ken5,Hayward Nicholas K.5,Jene Nicholas2,Dobrovic Alexander234,Pearson Richard B.146,Christensen James G.7,Randolph Sophia7,McArthur Grant A.14,Sheppard Karen E.146

Affiliation:

1. Research Division; Peter MacCallum Cancer Centre; East Melbourne Vic. Australia

2. Pathology Department; Peter MacCallum Cancer Centre; East Melbourne Vic. Australia

3. Ludwig Institute for Cancer Research; Olivia Newton John Cancer and Wellness Centre; Melbourne Vic. Australia

4. Sir Peter MacCallum Department of Oncology; University of Melbourne; Parkville Vic. Australia

5. Oncogenomics Laboratory; QIMR Berghofer Medical Research Institute; Brisbane Qld Australia

6. Department of Biochemistry and Molecular Biology; University of Melbourne; Parkville Vic. Australia

7. Pfizer Global Research and Development; La Jolla Laboratories; San Diego CA USA

Publisher

Wiley

Subject

Dermatology,General Biochemistry, Genetics and Molecular Biology,Oncology

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