Contact allergens in African countries: A review of published patch test studies

Author:

Bonefeld Nikolaj Menné1,Menné Torkil2,Ahrensbøll‐Friis Ulrik2ORCID,Gadsbøll Anne‐Sofie Østergaard1,Wang Christian William3,Theander Thor Grundtvig3,Masenga Elisante John4,Mavura Daudi4,Ødum Niels1,Bonefeld Charlotte Menné1ORCID,Geisler Carsten1ORCID

Affiliation:

1. LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark

2. National Allergy Research Centre, Department of Dermato‐Allergology Copenhagen University Hospital Herlev‐Gentofte Hellerup Denmark

3. Centre for Medical Parasitology, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark

4. Regional Dermatology Training Centre, Kilimanjaro Christian Medical Centre Moshi Tanzania

Abstract

AbstractOnly few studies on contact allergy in African countries have been published. The aim of the present study was to provide an overview of the most common contact allergens identified by the use of patch tests in African countries based on a review of the existing literature. A total of twenty‐four publications from eight African countries were initially identified by search in PubMed. The abstracts and method sections were screened, and 15 studies in which patch tests were actually used to identify the allergen causing the allergic contact dermatitis (ACD) were finally selected. Nickel, cobalt, chromium, fragrance mix and p‐tert‐butylphenol‐formaldehyde resin were the dominating contact allergens responsible for 40%–90% of the positive patch test reactions. This study indicates that a targeted effort directed towards prevention, avoidance and regulation of reliably identified contact allergens could reduce the disease burden of ACD considerable in some African countries.

Funder

LEO Fondet

Publisher

Wiley

Subject

Dermatology,Immunology and Allergy

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