Tacrolimus dose, blood concentrations and acute nephrotoxicity, but not CYP3A5/ABCB1 genetics, are associated with allograft tacrolimus concentrations in renal transplant recipients

Author:

Sallustio Benedetta C.12ORCID,Noll Benjamin D.3,Hu Rong4,Barratt Daniel T.2,Tuke Jonathan56,Coller Janet K.2ORCID,Russ Graeme R.7,Somogyi Andrew A.2ORCID

Affiliation:

1. Department of Clinical Pharmacology Basil Hetzel Institute, The Queen Elizabeth Hospital Woodville South SA 5011 Australia

2. Discipline of Pharmacology, Adelaide Medical School University of Adelaide Adelaide SA 5000 Australia

3. School of Pharmacy and Medical Sciences University of South Australia Australia Adelaide SA 5000 Australia

4. Department of Pharmacy, Guangzhou Women's and Children's Medical Centre Guangzhou Medical University Guangzhou China

5. ARC Centre for Excellence for Mathematical and Statistical Frontiers School of Mathematical Sciences Adelaide SA 5000 Australia

6. School of Mathematical Sciences Adelaide SA 5000 Australia

7. Central Northern Adelaide Renal and Transplantation Services, Royal Adelaide Hospital Adelaide SA 5000 Australia

Funder

Australian Research Council

National Health and Medical Research Council

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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