Innate IFN‐lambda responses to dsRNA in the human infant airway epithelium and clinical regulatory factors during viral respiratory infections in early life

Author:

Salka Kyle1,Arroyo Maria1,Chorvinsky Elizabeth1,Abutaleb Karima1,Perez Geovanny F.1,Wolf Seth1,Xuchen Xilei1,Weinstock Jered1,Gutierrez Maria J.2,Pérez‐Losada Marcos34,Pillai Dinesh K.1,Nino Gustavo1ORCID

Affiliation:

1. Division of Pediatric Pulmonary and Sleep Medicine. Children’s National Medical Center George Washington University Washington DC USA

2. Division of Pediatric Allergy and Immunology Johns Hopkins University Baltimore MD USA

3. Computational Biology Institute Department of Biostatistics and Bioinformatics Milken Institute School of Public Health George Washington University Washington DC USA

4. CIBIO‐InBIO Centro de Investigação em Biodiversidade e Recursos Genéticos Universidade do Porto Vairão Portugal

Funder

National Institute of Allergy and Infectious Diseases

National Heart, Lung, and Blood Institute

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference48 articles.

1. Innate immunity in the respiratory epithelium;Parker D;Am J Respir Cell Mol Biol,2011

2. Airway Epithelial Orchestration of Innate Immune Function in Response to Virus Infection;Ritchie AI;A Focus on Asthma. Ann Am Thorac Soc,2016

3. Rhinovirus‐induced airway disease: a model to understand the antiviral and Th2 epithelial immune dysregulation in childhood asthma;Perez GF;J Investig Med,2015

4. The sentinel role of the airway epithelium in asthma pathogenesis;Holgate ST;Immunol Rev,2011

5. Bronchial epithelium in children: a key player in asthma;Carsin A;Eur Respir Rev,2016

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