Evidence that the pregnane X and retinoid receptors PXR, RAR and RXR may regulate transcription of the transporterhOCT1in chronic myeloid leukaemia cells-Reference-Cited by-同舟云学术

Evidence that the pregnane X and retinoid receptors PXR, RAR and RXR may regulate transcription of the transporterhOCT1in chronic myeloid leukaemia cells

Published:2014-07-31 Issue:1 Volume:94 Page:74-78
ISSN:0902-4441
Container-title:European Journal of Haematology
language:en
Short-container-title:Eur J Haematol

Author:

Austin Gemma¹,Holcroft Alison¹,Rinne Natasha¹,Wang Lihui¹,Clark Richard E.¹

Affiliation:

1. Section of Haematology; Department of Molecular and Clinical Cancer Medicine; University of Liverpool; Liverpool UK

Publisher

Wiley

Subject

Hematology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/ejh.12409/fullpdf

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2. EVI-1 oncogene expression predicts survival in chronic-phase CML patients resistant to imatinib treated with second-generation tyrosine kinase inhibitors;Daghistani;Blood,2010

3. Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia;Wang;Clin Pharmacol Ther,2008

4. Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity;White;Blood,2007

5. Genomic analysis of the nuclear receptor family: new insights into structure, regulation, and evolution from the rat genome;Zhang;Genome Res,2004

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