Affiliation:
1. Division of Animal and Dairy Science Chungnam National University Daejeon South Korea
2. Hanwoo Research Institute National Institute of Animal Science Pyeongchang South Korea
3. Department of Beef Science Korea National University of Agriculture and Fisheries Wanju South Korea
4. Quantomic Research and Solution Daejeon South Korea
5. School of Environmental and Rural Science University of New England Armidale New South Wales Australia
Abstract
AbstractMeat tenderness is considered the most important trait contributing to beef quality, level of consumer satisfaction, willingness to pay premium prices and industry profit. Genomic selection method would be helpful for genetic improvement of traits with low heritability and that are difficult to measure. The identification of core genes can aid genomic selection for complex traits with low heritability that are difficult to measure. We performed statistical analysis of associations between longissimus dorsi muscle tenderness and gene expression in 20 Hanwoo cattle, using Warner–Bratzler shear force and RNAseq data, respectively. We found a total of 166 core genes, from which six (ASAP1, CAPN5, ELN, SUMF2, TTC8 and MGAT4A) were regulated by 16 cis‐expression quantitative trait loci (eQTL) SNPs. Notably, we found that a cis‐eQTL SNP of the ELN gene contained an MFZ‐1 binding site in its putative promoter region. These findings provide useful information for genomic prediction of beef tenderness in Hanwoo cattle.
Funder
Rural Development Administration
National Research Foundation of Korea
Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries
Subject
Genetics,Animal Science and Zoology,General Medicine