Dynamic changes in innate immune responses during direct-acting antiviral therapy for HCV infection

Author:

Holmes Jacinta A.12ORCID,Carlton-Smith Charles1,Kim Arthur Y.3,Dumas Emily O.4,Brown Joelle1,Gustafson Jenna L.1,Lauer Georg M.1,Silva Sakuni T.1,Robidoux Maxwell1,Kvistad Daniel1,Alatrakchi Nadia1,Tonnerre Pierre1,Cohen Daniel E.4,Zhang Hongtao4,Shulman Nancy S.4,Chung Raymond T.1

Affiliation:

1. Liver Center and Gastrointestinal Division; Department of Medicine; Massachusetts General Hospital; Harvard Medical School; Boston Massachusetts

2. Department of Gastroenterology; St Vincent's Hospital; University of Melbourne; Fitzroy Victoria Australia

3. Division of Infectious Diseases; Department of Medicine; Massachusetts General Hospital; Harvard Medical School; Boston Massachusetts

4. AbbVie Inc; North Chicago Illinois

Funder

AbbVie

National Institutes of Health

Massachusetts General Hospital

Publisher

Wiley

Subject

Virology,Infectious Diseases,Hepatology

Reference42 articles.

1. WHO Global hepatitis report 2017 Hepatitis https://www.who.int/hepatitis/publications/global-hepatitis-report2017/en/

2. The global burden of hepatitis C;Lavanchy;Liver Int,2009

3. Innate and adaptive immune responses in HCV infections;Heim;J Hepatol,2014

4. Interferon signaling and treatment outcome in chronic hepatitis C;Sarasin-Filipowicz;Proc Natl Acad Sci USA,2008

5. Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C;Honda;Gastroenterology,2010

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