Outcomes in 370 patients with mantle cell lymphoma treated with ibrutinib: a pooled analysis from three open-label studies

Author:

Rule Simon1ORCID,Dreyling Martin2,Goy Andre3,Hess Georg4,Auer Rebecca5,Kahl Brad6,Cavazos Nora7,Liu Black8,Yang Shiyi9,Clow Fong7,Goldberg Jenna D.9,Beaupre Darrin7,Vermeulen Jessica10,Wildgust Mark9,Wang Michael11

Affiliation:

1. Plymouth University Medical School; Plymouth UK

2. Klinikum der Universität München; Munich Germany

3. John Theurer Cancer Center at Hackensack University Medical Center; Hackensack NJ USA

4. University Medical School of the Johannes Gutenberg University; Mainz Germany

5. St. Bartholomew's Hospital; Barts Health NHS Trust; London UK

6. Washington University School of Medicine; St. Louis MO USA

7. Pharmacyclics; Sunnyvale CA USA

8. Janssen China Research & Development; Shanghai China

9. Janssen Research & Development; Raritan NJ USA

10. Janssen Research & Development; Leiden The Netherlands

11. The University of Texas MD Anderson Cancer Center; Houston TX USA

Funder

Janssen Research and Development

Publisher

Wiley

Subject

Hematology

Reference32 articles.

1. Activity of ibrutinib in mantle cell lymphoma patients with central nervous system relapse;Bernard;Blood,2015

2. Clinicopathologic features, management and outcomes of blastoid variant of mantle cell lymphoma: a Nebraska Lymphoma Study Group Experience;Bhatt;Leukemia & Lymphoma,2016

3. Updated efficacy including genetic and clinical subgroup analysis and overall safety in the phase 3 RESONATE™ trial of ibrutinib versus ofatumumab in previously treated chronic lymphocytic leukemia/small lymphocytic lymphoma;Brown;American Society of Hematology,2014

4. Bruton tyrosine kinase (BTK) and its role in B-cell malignancy;Buggy;International Reviews of Immunology,2012

5. Ibrutinib as initial therapy for patients with chronic lymphocytic leukemia;Burger;New England Journal of Medicine,2015

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