Randomized, Double-Blind Trial of Oral Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Chronic Noncancer Pain-Reference-Cited by-同舟云学术

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Randomized, Double-Blind Trial of Oral Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Chronic Noncancer Pain

Published:2017-02-10 Issue:6 Volume:17 Page:820-828
ISSN:1530-7085
Container-title:Pain Practice
language:en
Short-container-title:Pain Pract

Author:

Rauck Richard¹,Slatkin Neal E.²,Stambler Nancy³,Harper Joseph R.⁴,Israel Robert J.⁴

Affiliation:

1. The Center for Clinical Research; Winston-Salem North Carolina U.S.A

2. School of Medicine; University of California Riverside; Riverside California U.S.A

3. Progenics Pharmaceuticals, Inc.; New York New York U.S.A

4. Salix Pharmaceuticals; Raleigh North Carolina U.S.A

Funder

Salix Pharmaceuticals

BioDelivery Sciences International, Inc.

Boston Scientific Corporation, Inc.

Endo Pharmaceuticals Inc.

Mainstay Delivery

Pfizer

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/papr.12535/fullpdf

Reference21 articles.

1. Opioid-induced bowel dysfunction: epidemiology, pathophysiology, diagnosis, and initial therapeutic approach;Dorn;Am J Gastroenterol,2014

2. Emerging therapies for patients with symptoms of opioid-induced bowel dysfunction;Leppert;Drug Des Dev Ther,2015

3. The prevalence, severity, and impact of opioid-induced bowel dysfunction: results of a US and European patient survey (PROBE 1);Bell;Pain Med,2009

4. Gastrointestinal side effects in chronic opioid users: results from a population-based survey;Cook;Aliment Pharmacol Ther,2008

5. Opioid-induced bowel dysfunction: pathophysiology and potential new therapies;Kurz;Drugs,2003

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1. Insights into the Current and Possible Future Use of Opioid Antagonists in Relation to Opioid-Induced Constipation and Dysbiosis;Molecules;2023-11-24

2. Management of Constipation in Hospitalized Patients;Journal of Clinical Medicine;2023-09-23

3. Attrition of methylnaltrexone treatment-emergent adverse events in patients with chronic noncancer pain and opioid-induced constipation: a post hoc pooled analysis of two clinical trials;F1000Research;2023-07-11

4. Methylnaltrexone Treatment for Opioid-Induced Constipation in Patients with and without Cancer: Effect of Initial Dose;Journal of Pain Research;2023-07

5. Cumulative Laxation Response with Methylnaltrexone: Implications for Hospitalized Patients with Advanced Illness and Opioid-Induced Constipation;Current Therapeutic Research;2023

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