Pharmacokinetics and pharmacodynamics of PF-05190457: The first oral ghrelin receptor inverse agonist to be profiled in healthy subjects-Reference-Cited by-同舟云学术

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Pharmacokinetics and pharmacodynamics of PF-05190457: The first oral ghrelin receptor inverse agonist to be profiled in healthy subjects

Published:2016-10-29 Issue:2 Volume:83 Page:326-338
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Denney William S.¹,Sonnenberg Gabriele E.²,Carvajal-Gonzalez Santos²,Tuthill Theresa²,Jackson V. Margaret²

Affiliation:

1. Biotherapeutics Clinical Pharmacology; Pfizer Worldwide Research and Development; Cambridge Massachusetts 02139 USA

2. Cardiovascular, Metabolic, and Endocrine Diseases Research Unit; Pfizer Worldwide Research and Development; Cambridge Massachusetts 02139 USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.13127/fullpdf

Reference96 articles.

1. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands;Southan;Nucl Acids Res,2016

2. The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors;Alexander;Br J Pharmacol,2015

3. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans;Cummings;Diabetes,2001

4. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery;Cummings;N Engl J Med,2002

5. Ghrelin and obestatin levels in severely obese women before and after weight loss after roux-en-Y gastric bypass surgery;Roth;Obes Surg,2009

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