Protease-activated receptor 4 is more important than protease-activated receptor 1 for the thrombin-induced procoagulant effect on platelets
Author:
Affiliation:
1. Department of Clinical and Experimental Medicine; Linköping University; Linköping Sweden
2. Department of Clinical Chemistry; Linköping University; Linköping Sweden
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jth.13374/fullpdf
Reference29 articles.
1. A dual thrombin receptor system for platelet activation;Kahn;Nature,1998
2. Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin;Shapiro;J Biol Chem,2000
3. Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development;Vretenbrant;Thromb Haemost,2007
4. Superactivated platelets: thrombus regulators, thrombin generators, and potential clinical targets;Mazepa;Arterioscler Thromb Vasc Biol,2013
5. Generation of prothrombin-converting activity and the exposure of phosphatidylserine at the outer surface of platelets;Bevers;Eur J Biochem,1982
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