Intracranial haemorrhage in children and adolescents with severe haemophilia A or B - the impact of prophylactic treatment

Author:

Andersson Nadine G.1ORCID,Auerswald Günter2,Barnes Chris3,Carcao Manuel4ORCID,Dunn Amy L.5,Fijnvandraat Karin6,Hoffmann Marianne7,Kavakli Kaan8,Kenet Gili9,Kobelt Rainer10,Kurnik Karin11,Liesner Ri12,Mäkipernaa Anne13,Manco-Johnson Marilyn J.14,Mancuso Maria E.15ORCID,Molinari Angelo C.16,Nolan Beatrice17,Perez Garrido Rosario18,Petrini Pia19,Platokouki Helen E.20,Shapiro Amy D.21,Wu Runhui22,Ljung Rolf23

Affiliation:

1. Centre for Thrombosis and Haemostasis; Skåne University Hospital; Malmö Sweden

2. Klinikum Bremen-Mitte; Professor Hess Children's Hospital; Bremen Germany

3. Haematology; Royal Children's Hospital; Melbourne Vic. Australia

4. Division of Haematology/Oncology; Hospital for Sick Children; Toronto ON Canada

5. Division of Hematology, Oncology and Bone Marrow Transplant; Nationwide Children's Hospital and Ohio State University School of Medicine; Columbus OH USA

6. Department of Paediatric Haematology; Academic Medical Centre; University of Amsterdam; Amsterdam The Netherlands

7. Department of Pediatrics and Adolescent Medicine; University Hospital Rigshospitalet; Copenhagen Denmark

8. Department of Haematology; Ege University Children's Hospital; Izmir Turkey

9. National Haemophilia Centre; Tel Hashomer and the Sackler Medical School; Tel Aviv University; Tel Aviv Israel

10. Hämophiliezentrum; Wabern and Children's Hospital of the University of Bern; Bern Switzerland

11. Dr. von Hauner Children's Hospital; University of Munich; Munich Germany

12. Great Ormond Street Hospital for Children NHS Foundation Trust; Haemophilia Centre; London UK

13. Children's Hospital and Haematology; Cancer Center; Helsinki University Hospital; University of Helsinki; Helsinki Finland

14. Department of Pediatrics; University of Colorado; Aurora CO USA

15. Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre; Fondazione IRCCS Ca' Granda; Milan Italy

16. Dipartimento di Ematologia ed Oncologia; Unità Trombosi ed Emostasi; Ospedale Pediatrico Giannina Gaslini; Genoa Italy

17. Our Lady's Children's Hospital; Dublin Ireland

18. Haemophilia Unit; Hospital Universitario Virgen del Rocío; Sevilla Spain

19. Department of Paediatrics; Clinic of Coagulation Disorders; Karolinska Hospital; Stockholm Sweden

20. Haemophilia-Haemostasis Unit; St. Sophia Children's Hospital; Athens Greece

21. Indiana Hemophilia and Thrombosis Center; Indianapolis IN USA

22. Hematology-Oncology Center; Beijing Children's Hospital; Capital Medical University; National Center for Children's Health; Beijing China

23. Department of Clinical Sciences Lund; Lund University; Lund Sweden

Funder

Bayer Award

Vetenskapsrådet

Publisher

Wiley

Subject

Hematology

Reference41 articles.

1. Head trauma in hemophilia. A prospective study;Andes;Archives of Internal Medicine,1984

2. Intracranial haemorrhage among a population of haemophilic patients in Brazil;Antunes;Haemophilia,2003

3. Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized;Astermark;British Journal of Haematology,1999

4. Prophylaxis for hemophilia in the era of extended half-life factor VIII/factor IX products;Berntorp;Seminars in Thrombosis and Hemostasis,2016

5. Modern treatment of haemophilia;Berntorp;Bulletin of the World Health Organization,1995

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