Cucurbitacin I exhibits anticancer efficacy through induction of apoptosis and modulation of <scp>JAK</scp> / <scp>STAT3</scp> , <scp>MAPK</scp> / <scp>ERK</scp> , and <scp>AKT</scp> / <scp>mTOR</scp> signaling pathways in <scp>HepG2</scp> cell line-Reference-Cited by-同舟云学术

Cucurbitacin I exhibits anticancer efficacy through induction of apoptosis and modulation of JAK / STAT3 , MAPK / ERK , and AKT / mTOR signaling pathways in HepG2 cell line

Published:2022-07-22 Issue:10 Volume:46 Page:
ISSN:0145-8884
Container-title:Journal of Food Biochemistry
language:en
Short-container-title:Journal of Food Biochemistry

Author:

Üremiş Nuray¹,Üremiş Muhammed Mehdi¹,Çiğremiş Yılmaz²,Tosun Emir³,Baysar Ahmet³,Türköz Yusuf¹

Affiliation:

1. Department of Medical Biochemistry, Faculty of Medicine Inonu University Malatya Turkey

2. Department of Medical Biology and Genetics, Faculty of Medicine Inonu University Malatya Turkey

3. Department of Chemical Engineering, Faculty of Engineering Inonu University Malatya Turkey

Publisher

Hindawi Limited

Subject

Cell Biology,Pharmacology,Food Science,Biophysics

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jfbc.14333

Reference61 articles.

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2. Analgesic and antipyretic effects ofEcballium elaterium (L.) A. Richard. Extract in rodents

3. Preliminary phytochemical analysis and evaluation of in vitro antioxidant, antiproliferative, antidiabetic, and anticholinergics effects of endemic Gypsophila taxa from Turkey

4. Cellular and molecular mechanisms of hepatocellular carcinoma: an update

5. Discovery of JSI‐124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice;Blaskovich M. A.;Cancer Research,2003

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