The calcium-activated potassium channel KCa3.1 plays a central role in the chemotactic response of mammalian neutrophils

Author:

Henríquez C.1,Riquelme T. T.2,Vera D.2,Julio-Kalajzić F.23,Ehrenfeld P.4,Melvin J. E.5,Figueroa C. D.4,Sarmiento J.6,Flores C. A.2

Affiliation:

1. Instituto de Farmacología; Facultad de Medicina Veterinaria; Universidad Austral de Chile; Valdivia Chile

2. Centro de Estudios Científicos (CECs); Valdivia Chile

3. Pontificia Universidad Católica de Valparaíso; Valparaíso Chile

4. Institutos de Anatomía; Histología y Patología; Universidad Austral de Chile; Valdivia Chile

5. Secretory Mechanisms and Dysfunction Section; National Institute of Dental and Craniofacial Research; National Institutes of Health; Bethesda MD USA

6. Instituto de Fisiología; Facultad de Medicina; Universidad Austral de Chile; Valdivia Chile

Funder

Fondo Nacional de Desarrollo Científico y Tecnológico

Centro de Estudios Científicos

Centers of Excellence Base Financing Program of Conicyt

Publisher

Wiley

Subject

Physiology

Reference54 articles.

1. Neutrophil function: from mechanisms to disease;Amulic;Annu Rev Immunol,2012

2. Characterization of fMet-Leu-Phe receptor-mediated Ca2 +  influx across the plasma membrane of human neutrophils;Andersson;Mol Pharmacol,1986

3. Physiological roles of the intermediate conductance, Ca2 + -activated potassium channel Kcnn4;Begenisich;J Biol Chem,2004

4. Regulation of superoxide production in neutrophils: role of calcium influx;Brechard;J Leukoc Biol,2008

5. Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines;Burgos;Vet Immunol Immunopathol,2011

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