Noninvasive finger plethysmography for continuous blood pressure monitoring in patients with left ventricular assist device

Author:

Favilla Christopher G.1ORCID,Carter Sarah C.1,Atluri Pavan2,Reehal Navpreet1,Genuardi Michael V.3

Affiliation:

1. Department of Neurology University of Pennsylvania Philadelphia Pennsylvania USA

2. Department of Cardiothoracic Surgery University of Pennsylvania Philadelphia Pennsylvania USA

3. Division of Cardiology, Department of Medicine University of Pennsylvania Philadelphia Pennsylvania USA

Abstract

AbstractBackgroundAccurate blood pressure (BP) measurement remains challenging in patients with HeartMate 3™ left ventricular assist devices (HM3 LVADs). The Finapres® NOVA is a promising non‐invasive continuous BP monitor that uses the volume clamp method via a finger cuff, so here we aimed to validate the instrument in HM3 patients.MethodsIn a single‐center cohort, BP was monitored in 15 patients within 72 h following HM3 implantation. A radial artery catheter quantified arterial blood pressure (ABP), while the NOVA measured finger arterial pressure (fiAP) and reconstructed brachial artery pressure (reBAP). Waveforms were recorded for 10 min, and mean values were calculated in 15‐s intervals.ResutsfiAP and ABP were moderately correlated during both the first (ICC 0.61, p = 0.04) and final measurements (ICC 0.66, p = 0.03). reBAP and ABP were strongly correlated during both the first (ICC 0.81, p = 0.002) and final measurements (ICC 0.83, p = 0.001). Both NOVA‐derived values may underestimate low BP values while overestimating relatively high BP values. The reBAP was within 5 mm Hg of the ABP in 40% of patients (and within 10 mm Hg in 67%).ConclusionsThis pilot represents the first evidence in support of the Finapres® NOVA for non‐invasive BP measurement in select patients with HM3 LVADs. The instrument may provide useful data during BP medication adjustments or pump titration, but despite the correlation between the non‐invasive reBAP and invasive ABP, individual‐level inaccuracy may be clinically meaningful. Further investigation is needed to clarify these limitations and optimize accuracy before widespread adoption in this unique patient population.

Funder

American Heart Association

Institute for Translational Medicine and Therapeutics

National Institute of Neurological Disorders and Stroke

Publisher

Wiley

Subject

Biomedical Engineering,General Medicine,Biomaterials,Medicine (miscellaneous),Bioengineering

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