The multidrug resistance transporters CgTpo1_1 and CgTpo1_2 play a role in virulence and biofilm formation in the human pathogenCandida glabrata

Author:

Santos Rui12,Costa Catarina12,Mil-Homens Dalila12,Romão Daniela12,de Carvalho Carla C.C.R.12,Pais Pedro12,Mira Nuno P.12,Fialho Arsénio M.12,Teixeira Miguel C.12ORCID

Affiliation:

1. Department of Bioengineering, Instituto Superior Técnico; Universidade de Lisboa; Lisbon Portugal

2. Biological Sciences Research Group, IBB - Institute for Bioengineering and Biosciences; Instituto Superior Técnico; Lisbon Portugal

Funder

FCT-Portuguese Foundation for Science and Technology

Fundação para a Ciência e a Tecnologia

Federación Española de Enfermedades Raras

Publisher

Hindawi Limited

Subject

Virology,Immunology,Microbiology

Reference60 articles.

1. Reduced virulence of Candida albicans mutants affected in multidrug resistance;Becker;Infection and Immunity,1995

2. Candida albicans biofilms: Building a heterogeneous, drug-tolerant environment;Bonhomme;Current Opinion in Microbiology,2013

3. Two unlike cousins: Candida albicans and C. glabrata infection strategies;Brunke;Cellular Microbiology,2013

4. The yeast ABC transporter Pdr18 (ORF YNR070w) controls plasma membrane sterol composition, playing a role in multidrug resistance;Cabrito;The Biochemical Journal,2011

5. Candida glabrata STE12 is required for wild-type levels of virulence and nitrogen starvation induced filamentation;Calcagno;Molecular Microbiology,2003

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