PERSPECTIVE: DETECTING ADAPTIVE MOLECULAR POLYMORPHISM: LESSONS FROM THE MHC
Author:
Publisher
Wiley
Subject
General Agricultural and Biological Sciences,Genetics,Ecology, Evolution, Behavior and Systematics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.0014-3820.2003.tb00580.x/fullpdf
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1. Common chimpanzees have greater diversity than humans at two of the three highly polymorphic MHC class I genes
2. Linkage disequilibrium and age estimates of a deletion polymorphism (1597ΔC) in HLA-G suggest non-neutral evolution
3. Resistance to three pathogens in the endangered winter-run chinook salmon (Oncorhynchus tshawytscha): effects of inbreeding and major histocompatibility complex genotypes
4. A strong signature of balancing selection in the 5' cis-regulatory region of CCR5
5. Analysis of HLA genes and haplotypes in Ainu (from Hokkaido, northern Japan) supports the premise that they descent from Upper Paleolithic populations of East Asia
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