Reflections on MUC1 glycoprotein: the hidden potential of isoforms in carcinogenesis

Author:

Sousa Andreia M.12,Grandgenett Paul M.3,David Leonor124,Almeida Raquel1245,Hollingsworth Michael Anthony3,Santos-Silva Filipe124

Affiliation:

1. i3S-Institute of Research and Innovation in Health; University of Porto; Porto Portugal

2. IPATIMUP-Institute of Molecular Pathology and Immunology of the University of Porto; Porto Portugal

3. Eppley Institute for Research in Cancer and Allied Disease; Omaha NE USA

4. Faculty of Medicine of the University of Porto; Porto Portugal

5. Department of Biology, Faculty of Sciences of the University of Porto; Porto Portugal

Publisher

Wiley

Subject

Microbiology (medical),General Medicine,Immunology and Allergy,Pathology and Forensic Medicine

Reference123 articles.

1. Intestinal mucins in health and disease;Forstner;Digestion,1978

2. MUC1 and the MUCs: a family of human mucins with impact in cancer biology;Baldus;Crit Rev Clin Lab Sci,2004

3. Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7);Bobek;J Biol Chem,1993

4. Human mucin gene MUC5B, the 10.7-kb large central exon encodes various alternate subdomains resulting in a super-repeat. Structural evidence for a 11p15.5 gene family;Desseyn;J Biol Chem,1997

5. Human mucin gene MUC5AC: organization of its 5′-region and central repetitive region;Escande;Biochem J,2001

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