An expedited model for identifying potential patients with periodic leg movements

Author:

Chen Po‐Yueh12,Lin Shang‐Yang3,Wu Chung‐Sheng4,Hung Shih‐Han125,Chen David Hsin‐Kuang6,Liu Wen‐Te78,Lin Yi‐Chih28910ORCID

Affiliation:

1. Department of Otolaryngology Wan Fang Hospital, Taipei Medical University Taipei Taiwan

2. Department of Otolaryngology, School of Medicine, College of Medicine Taipei Medical University Taipei Taiwan

3. Center for Artificial Intelligence and Advanced Robotics National Taiwan University Taipei Taiwan

4. Department of Primary Care Medicine Shuang‐Ho Hospital, Taipei Medical University New Taipei City Taiwan

5. International Master/Ph.D. Program in Medicine, College of Medicine Taipei Medical University Taipei Taiwan

6. Department of Medical Education Shuang‐Ho Hospital, Taipei Medical University New Taipei City Taiwan

7. Department of Chest Medicine Shuang Ho Hospital, Taipei Medical University New Taipei City Taiwan

8. Sleep Center Shuang Ho Hospital, Taipei Medical University New Taipei City Taiwan

9. Department of Otolaryngology Shuang Ho Hospital, Taipei Medical University New Taipei City Taiwan

10. School of Public Health, College of Public Health Taipei Medical University Taipei Taiwan

Abstract

SummaryPeriodic leg movements during sleep (PLMS) may have crucial consequences in adults. This study aimed to identify baseline characteristics, symptoms, or questionnaires that could help to identify sleep‐disordered breathing patients with significant PLMS. Patients aged 20–80 years who underwent polysomnography for assessing sleep disturbance were included. Various factors such as sex, age, body measurements, symptoms, apnea–hypopnea index (AHI), and sleep quality scales were analysed to determine the presence of PLMS. The study included 1480 patients with a mean age of 46.4 ± 13.4 years, among whom 110 (7.4%) had significant PLMS with a PLM index of 15 or higher. There were no significant differences observed in terms of sex or BMI between patients with and without significant PLMS. However, the odds ratios (OR) for PLMS were 4.33, 4.41, and 4.23 in patients who were aged over 50 years, had insomnia, or had an ESS score of less than 10, respectively. Notably, the OR increased up to 67.89 times in patients who presented with all three risk factors. Our analysis identified significant risk factors for PLMS: age over 50, self‐reported insomnia, and lower daytime sleepiness levels. These findings aid in identifying potential PLMS patients, facilitating confirmatory examinations and managing associated comorbidities.

Publisher

Wiley

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