Depletion of Foxp3+T Cells Abrogates Tolerance of Skin and Heart Allografts in Murine Mixed Chimeras Without the Loss of Mixed Chimerism-Reference-Cited by-同舟云学术

Depletion of Foxp3+T Cells Abrogates Tolerance of Skin and Heart Allografts in Murine Mixed Chimeras Without the Loss of Mixed Chimerism

Published:2014-08-25 Issue:10 Volume:14 Page:2263-2274
ISSN:1600-6135
Container-title:American Journal of Transplantation
language:en
Short-container-title:

Author:

Shinoda K.¹²,Akiyoshi T.³,Chase C. M.¹²,Farkash E. A.³,Ndishabandi D. K.³,Raczek C. M.³,Sebastian D. P.³,Della Pelle P.³,Russell P. S.¹²⁴,Madsen J. C.¹²⁴,Colvin R. B.¹³⁵,Alessandrini A.¹²⁴

Affiliation:

1. Transplant Center; Massachusetts General Hospital; Boston MA

2. Department of Surgery; Massachusetts General Hospital; Boston MA

3. Department of Pathology; Massachusetts General Hospital; Boston MA

4. Department of Surgery; Harvard Medical School; Boston MA

5. Department of Pathology; Harvard Medical School; Boston MA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology (medical),Transplantation,Immunology and Allergy

Reference33 articles.

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2. Additional monoclonal antibody (mAB) injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3-Gy whole body irradiation;Tomita;Transplantation,1996

3. Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non-myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance;Wekerle;Transplantation,1999

4. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment;Wekerle;Nat Med,2000

5. Mixed chimerism as an approach for the induction of transplantation tolerance;Wekerle;Transplantation,1999

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